Vulvovaginitis is the inflammation of your vulva and vagina. It is also called vaginitis or vulvitis. It is a common condition – at least one-third of women will have it during their lifetime. It shows up most often during your reproductive years.

Vaginitis is the general term that characterizes a spectrum of vaginal disorders caused by infections, inflammation, or changes in the normal vaginal flora. Symptoms include abnormal vaginal discharge, odours, itching, pain, dysuria, discomfort, and dyspareunia.

The most common types of vaginitis are caused by aerobic or parasitic bacteria (Trichomonas vaginalis, Gardnerella vaginalis and Candida albicans) and account for about 70% of cases.

Nonspecific vaginitis (also called vaginal dysbiosis) is a disorder of the vaginal microbiome. Recent studies show that vaginal dysbiosis affects the acquisition of human papilloma virus, persistence and progression to associated cervical premalignment.

30% of cases are non-specific vaginitis and have various causes (irritant, allergic or traumatic), including atrophic vaginitis, inflammatory desquamative vaginitis and irritant/allergic vaginitis.

There are several other types of non-infectious vaginitis in clinical practice: inflammatory vaginitis, squamous inflammatory vaginitis, irritating vaginitis, atrophic vaginitis, cytolytic vaginitis, and aerobic vaginitis.

The main factors that can create a major risk of developing non-infectious vulvovaginitis are:

• sexual contact (the formation of microscopic abrasions due to inadequate lubrication would favor the penetration of external agents, a possible source of sensitization);
• hygiene habits (excessive use of intimate soaps and vaginal washings significantly increases the risk of contracting irritating vulvovaginitis);
• clothing (the habit of wearing very tight clothes, especially if they are made of a synthetic material, would contribute to changing the vaginal ecosystem, making it more sensitive);
• psychological factors (some women with recurrent non-infectious vulvovaginitis have an unsatisfactory sex life or often have depressive episodes).
• In some cases, vaginitis results from organisms that are transmitted between the sexual partners, vaginal dryness and lack of estrogen.
• Low estrogen levels in women after menopause can cause vaginal dryness and thinning of the skin of the vagina and vulva. These factors may lead to or worsen genital itching and burning.

Administration of CERVIRON^® significantly alleviates the symptoms of symptomatic, non-specific, non-infectious vaginitis, and its administration can be considered safe. CERVIRON^® can be used as long-term supportive therapy, either as a stand-alone treatment or in combination with other oral therapies with antibiotics, antifungals or antivirals. CERVIRON^® supportive therapy may be prescribed for 10 or 15 consecutive days. While balancing the vaginal pH, CERVIRON^® reduces vaginal inflammation and improves the vaginal discharge aspect after 3 months of therapy.